what antihistamines are safe for high blood pressure

Antihistamines can also cause dry mouth, feelings of fatigue, constipation and dizziness. As with any medication, it is best to check with your doctor before starting an antihistamine. Histamine and H1-antihistamines: celebrating a century of progress. 2015;15:2. doi:10.1186/1471-2318-15-2. Among over-the-counter cold remedies, decongestants cause the most concern for people who have high blood pressure. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, How to Exercise Outside When You Have Allergies, An Allergy-Free Vacation: It's Possible With Planning, Blocking Allergy Symptoms: How Pretreatment Works. Allergy, histamine and antihistamines. Antihistamines such as … Most of them seem to be safe if you have high blood pressure-- but again, ask to make sure. The drugs used to treat high blood pressure are effective and relatively safe, and most are available as low-cost generics. Used to treat allergic-type reactions due to perennial or seasonal allergic rhinitis … Antihistamines -- both over-the-counter and prescription -- can lessen the symptoms of allergies, like sneezing, runny nose, itching and some headaches. doi:10.3390/ijms20071733. Jennifer Hanes is a nationally recognized physician and best-selling author. If you have high blood pressure… However, be sure to check with a doctor before taking any medications, even … © 2005 - 2021 WebMD LLC. Can antihistamines cause weight gain? Urinary retention. Alternatively, she may prescribe a nasal antihistamine, such as azelastine (Astelin) or olopatadine (Patanol), or a nasal corticosteroid, such as beclomethasone (Beconase) or fluticasone (Flonase). Zyrtec is less likely … To lessen the side effects of antihistamines and further reduce allergy symptoms, some allergy medicines combine an antihistamine with a decongestant, such as pseudoephedrine or phenylephrine. Zyrtec is a popular over-the-counter antihistamine medicine (a brand-name version of cetirizine) and generally considered a safe choice for those with high blood pressure. These decongestants can be phenylephrine or pseudoephedrine or oxymetazoline. Many over-the-counter brand-name antihistamines are available, … JAMA Intern Med. Saline sprays are also another safe option that can loosen congestion and improve drainage. Many people with high blood pressure can safely take antihistamines to curb allergy symptoms, minding the drowsiness warning. In general that’s okay for most patients. Antihistamines are a class of agents that block histamine release … Church MK. Watch out for combination medications for allergies that include decongestant ingredients. BMC Geriatr. What are the conclusions from clinical trials and meta-analyses?Drug Des Devel Ther. "In general, antihistamines are safe in patients with high blood pressure and other forms of heart disease," explains Richard Krasuski, MD, director of adult congenital heart … That includes allergy drugs as well as many remedies for cold, flu, and sinus problems. All rights reserved. But it might be good … When histamine levels get too high or when histamine cannot break down … Some antihistamines, such as levocetirizine (Xyzal), require a prescription. Updated September 2015. To lessen the side effects of antihistamines and further reduce allergy symptoms, some allergy medicines combine an antihistamine with a decongestant, such as pseudoephedrine or phenylephrine. 2019;20(7). About 1 in 3 American women have high blood pressure and seasonal allergies affect many of them. It triggers a cascade of inflammatory chemicals, often resulting in sneezing, itchy eyes, coughing and runny nose. Antihistamines are the most common medication for allergies. The decongestant helps alleviate allergy symptoms by shrinking the blood vessels to relieve nasal and sinus pressure. Unfortunately, there is no one product that can be recommended to provide safe and effective relief of nasal congestion in all patients with high blood pressure. 3 If a patient with high blood pressure insists on taking a medication that includes … If you’re already taking medication for high blood pressure, combining that with an antihistamine can increase your heart rate and raise your blood pressure. American Academy of Otolaryngology – Head and Neck Surgery. 4 Many of the symptoms are treatable by antihistamines, which are safe for those with high blood pressure… Hon KL, Leung TF, Leung AK. Don't take decongestants unless your doctor tells you otherwise. Histamine is a compound the immune system releases as part of an allergic response. Allergic rhinitis is a condition in which patients exhibit a constellation of symptoms such as rhinorrhea, nasal congestion, nasal itching, paroxysms of sneezing, and ophthalmic itching. Alvarez CA, Mortensen EM, Makris UE, et al. Decongestants have been demonstrated, in some cases, to raise blood pressure, cause unstable heart rhythms and increase the heart rate above 100 beats per minute. Many are available over the counter, including diphenhydramine (Benadryl), loratadine (Claritin), cetirizine (Zyrtec) and fexofenadine (Allegra). ", UpToDate: "Definition, risk factors, and evaluation of resistant hypertension," "Diphenhydramine.". They may raise your blood pressure. Antihistamines -- both over-the-counter and prescription -- can lessen the symptoms of allergies, like sneezing, runny nose, itching and some headaches. Some read the warning label: "Do not use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or difficulty in urination due to enlargement of the prostate gland unless directed by a doctor." Many are available over the counter, including diphenhydramine (Benadryl), loratadine (Claritin), cetirizine (Zyrtec) and fexofenadine (Allegra). Hanes holds a doctorate in osteopathic medicine from the University of Health Sciences College of Osteopathic Medicine. Curr Allergy Asthma Rep 13, 203–208 (2013) doi:10.1007/s11882-013-0341-4, Gray SL, Anderson ML, Dublin S, et al. Histamine is a compound the immune system releases as part of an allergic response. Scaglione F. Safety profile of bilastine: 2nd generation H1-antihistamines. Nonsteroidal anti-inflammatory drugs (NSAIDs) is the blanket name for such OTC medications as aspirin (Bayer, Bufferin, St. Joseph), ibuprofen (Advil, Motrin), and naproxen sodium (Aleve). Most of them seem to be safe if you have high blood pressure -- but again, ask to make sure. Few heed it. Many people with high blood pressure can safely take antihistamines to curb allergy symptoms, minding the drowsiness warning. If you have high blood pressure, some antihistamine drugs could interact with your other medications or contain a decongestant ingredient that could be dangerous. It triggers a cascade of inflammatory chemicals, often resulting in sneezing, itchy eyes, coughing and runny nose. Allergens and allergic asthma. Over-the-counter cold remedies aren't off-limits if you have high blood pressure, but it's important to make careful choices. Make these tweaks to your diet, home, and lifestyle. If you experience chest pain, shortness of breath, dizziness or difficulty speaking, seek immediate medical attention. An antihistamine refers to the class of medications used to lower the effect of histamines. Phenylephrine. She is board-certified in both emergency medicine and integrative medicine, combining traditional and alternative treatments. Antihistamines … Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. So, it is not recommended in those with a hypertension diagnosis. Talk to your healthcare provider about your options. Antihistamines … 2017;241:321-331. doi:10.1007/164_2016_85. If you take an over-the-counter allergy product, look for one that doesn't contain pseudoephedrine or phenylephrine. Copyright © 2021 Leaf Group Ltd., all rights reserved. The most common decongestants are: pseudoephedrine phenylephrine You should avoid these if you have high blood pressure, especially if your blood pressure has been difficult to control. 2015;175(3):401-7. doi:10.1001/jamainternmed.2014.7663, Simons FE, Simons KJ. Benadryl is an … For those with high blood pressure, phenylephrine is an alternative to pseudoephedrine. First things first: Always check with your doctor or pharmacist before you start to take any medication -- for allergies, high blood pressure (or “hypertension,” as doctors call it), or anything else. But you should be careful when choosing an allergy medication because many contain an antihistamine as well as a decongestant, which can be dangerous if you have hypertension. The Problem: When taking a decongestant, heart rate and blood pressure go up, the heart beats stronger, blood vessels constrict in nasal passages reducing fluid build-up. While pharmacists often answer questions concerning products for relief of common cold symptoms, selecting appropriate products for the patient with hypertension is a challenge. Some antihistamines, such as levocetirizine (Xyza… The relationship between Benadryl and high blood pressure arises from the effect the medication has on blood vessels and also its interaction with hypertension medications. Int J Mol Sci. They also keep some high blood pressure drugs from working the way they should.Be careful, because many allergy medications contain antihistamines and a decongestant. They are in the same drug class known as nasal decongestants, which help relieve sinus congestion and pressure. Antihistamines, decongestants, and cold remedies. Your doctor may recommend taking these medications in the evening because they can cause drowsiness. And always check the active and inactive ingredient lists, because many medications are high in sodium, which also raises blood pressure. Upsides. J Allergy Clin Immunol. … Antihistamines and corticosteroids are generally safe for people with high blood pressure 3. But not for patients with high blood pressure… Asthma and Allergy Foundation of America. Histamine intolerance is the overproduction of histamine in the body or the inability to break it down. Antihistamines like Benadryl may not be effective or safe when you have high blood pressure. doi:10.1016/j.jaci.2011.09.005. They can cause trouble sleeping, headache, increased blood pressure and irritability. Decongestants are used for quick, temporary relief of nasal and sinus congestion. Can antihistamines cause high blood pressure? Handb Exp Pharmacol. An antihistamine refers to the class of medications used to lower the effect of histamines. They're not recommended for people with high blood pressure… 2014;8:839-50. doi:10.2147/DDDT.S39100, Çobanoğlu, B., Toskala, E., Ural, A. et al. If you have high blood pressure you may be able to safely lessen the symptoms of seasonal allergies by taking antihistamines. If you have high blood pressure, check with your doctor before taking an allergy medication to make sure it is safe … Association of skeletal muscle relaxers and antihistamines on mortality, hospitalizations, and emergency department visits in elderly patients: a nationwide retrospective cohort study. The U.S. Food and Drug Administration cautions that antihistamines can also slow reaction time and make you less able to focus. These side effects may be heightened if the antihistamine is taken along with certain antidepressants, pain medications or pills for stomach irritation. For patients who have high blood pressure, rhythm problems (palpitations), or who have severe blockages … 2012;16:1999–2005. Decongestants relieve nasal stuffiness by narrowing blood … Antihistamines are drugs that can relieve allergy symptoms such as runny nose, sneezing, and congestion. This increases blood pressure. Yes and Yes: Diphenhydramine (benadryl) can have a sedative and blood pressure lowering effect. Antihistamines combined with a decongestant are often labelled with a "D" ending, such as Zyrtec-D and Claritin-D. Ask your pharmacist to check the ingredients for you. WebMD does not provide medical advice, diagnosis or treatment. // Leaf Group Lifestyle, The Best Allergy Medicine for High Blood Pressure, Anti-Inflammatory and Antihistamine Comparison, The National Heart, Lung, and Blood Institute: The Seventh Report on the Prevention, Detection, Evaluation and Treatment of High Blood Pressure, Drugs.com: Pseudoephedrine Side Effects for the Healthcare Professional, Drugs.com: Monograph: Cetirizine Hydrochloride, U.S. Food and Drug Administration: Allergy Meds Could Affect Your Driving, Yamauchi K, Ogasawara M. The role of histamine in the pathophysiology of asthma and the clinical efficacy of antihistamines in asthma therapy. For allergy sufferers with heart disease, medicines such as Allegra, Zyrtec or Claritin … Always read the label and follow the directions. Clinical effectiveness and safety of montelukast in asthma. That's true for herbs and supplements, too. If you have high blood pressure, you should generally avoid decongestants, even if they are combined with an antihistamine. Histamine is a compound the immune system releases as part of an allergic response. American Heart Association: "Over-the-Counter Medications. But they can cause side effects, as listed in the table below. Eur Rev Med Pharmacol Sci. First-generation oral antihistamines, including diphenhydramine (Benadryl) and chlorpheniramine (Chlor-Trimeton), easily cross the blood-brain barrier and affect H1 … Antihistamines are the most common medication for allergies. Fortunately, if you have high blood pressure, there are safer alternatives when cold and allergy season come around. ", Harvard Medical School: "Don't Let Decongestants Squeeze Your Heart. 2011;128(6):1139-1150.e4. Role of leukotriene antagonists and antihistamines in the treatment of allergic rhinitis. Increased urinary retention—meaning that your bladder doesn’t empty all …

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